About the Book:

"A Novel Chemotherapeutic Drug Poly-L-Lysine against Cancer Therapy - A Research based Study" offers a fresh perspective on cancer therapy. This research-based study delves into the potential of L-lysine as a novel chemotherapeutic drug that could revolutionize cancer treatment. The authors present the results of their studies, which showcase Poly-L-lysine's anti-angiogenesis properties and its potential in treating angiogenesis-related diseases. The book features eleven comprehensive chapters that provide an in-depth analysis of the research, including the apoptotic and anticancer effects of L-lysine in mice models, as well as its anti-proliferative and antiangiogenic properties. At the same time, the book shares fascinating insights about the history of cancer and the medical community's ongoing efforts to find a cure.”

Contents:

1.    Introduction

2.    Literature Review

3.    Aim and Objectives of the Study

4.    General Remarks

5.    Apoptosis Effect on EAC and in S-180 Tumour Model

6.    Evaluation of the Antioxidant and Antitumor Activity of Poly-L-Lysine in the Murine Malignant Tumour BALB/c Mice Model by Activating the Apoptosis

7.    The Effect of Anti-Propagation, Tumour-Angiogenic Repression and Down-Regulation of DAL Engendered Tumourigenesis by PLL

8.    Antiangiogenic Effect on B16F10 Tumour & 3D Cell Culture

9.    Summary of Research Work

10. Conclusion

11. Future Directions

About the Authors:

TK Chatterjee, the former UGC (Govt. of India) Research Scientist and retired Professor in the Department of Pharmaceutical Technology, Jadavpur University, Kolkata, has been dynamically engaged in Pharmacological and Toxicological research and teaching for the past three decades. Presently, he holds the post of Dean, School of Pharmacy at JIS University, Kolkata. He is the author of more than 160 research papers in journals of National and International repute. He has written multiple books entitled "Handbook on Laboratory Mice and Rats" (1993), "Herbal Options" (1st edition 1996, 2nd edition 1997, 3rd edition 1999), "Chemotherapy of Tropical Parasitic Infection" (1st edition1995, 2nd edition 1999), "Skin Diseases and Treatment" (1st edition 1999), "A handbook of Pharmacology" (2011). "Pharmacological Properties of Coccaniagrandis" (2012) "Medicinal Plant Abrusprecatorious L." (2012), "Anti-Diabetic Plant Steospermumsuaveolens (Roxb.) DC" (2012), "Rodents for Pharmacological Experiments" (2013), "Antioxidant and Anti-Diabetic Activities of Polyalthialongifolia Leaves" (2013), "Databook for Clinical Pharmacology" (2014), "Quintessence of Pharmacovigilance" (2017), "Essentials of Herbal options" (2020) and "Targeted Drug Therapy in Colon Cancer-An Evidence based Research" (2022) have attracted widespread appreciation from various organisations of Pharmaceutical & Medical communities. Presentation of his research at International conferences in Sweden, Germany, Belgium, U.K, Brazil, and USA are well documented. He has mentored more than twenty-seven Ph.D and forty-seven M.Pharm dissertation thesis the students. He is also a freelance Bio-Medical writer with renowned expertise. He has received multiple prestigious awards like Ram Mohan Puraskar, Aadi Samman, NIMA Award, Nagarjun Puraskar, Outstanding Scientist Award and Asia's Top 50 Academicians & Research Award 2022, National Excellence Award 2023, International Excellence Award 2023 and Indian Glory Award 2023 for his contributions to Pharmaceutical Sciences and Research. He is the holder of many patents (Granted & Pending). His research works were regarded in high esteem for embracing in-depth expertise on the relevant topics of his research.

Souvik Debnath, after completing his M.Sc in microbiology, did his Ph.D. under the supervision of Prof. T. K. Chatterjee at Jadavpur University. He obtained two prestigious funding at Jadavpur University to work in the laboratory for his Ph.D. research. He got the prestigious UGC-BSR Research Fellowship in Science for the Meritorious Student fellowship and joined Jadavpur University as a research scholar for his Ph.D. program.  He was also awarded by DST an outstanding scholarship known as SERB-OVDF and carried out his higher research at Purdue University, USA.  He has proven exceptional in every way during his Ph.D. graduate career there.