About the Book:

“Experimental Organic and Medicinal Chemistry: Principles and Practice, 2nd Edition.” of this comprehensive guide. Designed for pharmacy and allied field graduates, this book, "Experimental Organic and Medicinal Chemistry-Principles & Practice," is a treasure trove of synthetic and analytical approaches essential for both academic and industrial realms.

Embark on a journey through 64 enlightening chapters, where the art of synthesizing drugs and drug intermediates is unveiled alongside their pharmaceutical significance and underlying reaction mechanisms. Delve into the realm of green synthetic strategies, where alternative reagents and safety precautions take center stage, promising a sustainable approach to drug synthesis.

Contents:

1.     Laboratory Practices

2.     Laboratory Safety

3.     Acylation

4.     Alkylation

5.    Aromatic Electrophilic Subsitution

6.    Beckmann Rearrangement

7.    Bernthsen Synthesis

8.    Biginelli Synthesis

9.    Biltz Synthesis

10. Borsche-Drechsel Cyclization

11. Claisen Isoxazole Synthesis

12. Claisen-Schmidt Reaction

13. Diazotization Reaction

14. Erlenmeyer-Plochl Azlactone Synthesis

15. Fischer Indole Synthesis

16. Fischer-Speier Esterification

17. Haloform Reaction

18. Hantzsch 1,4-Dihydropyridine Synthesis

19. Hydrolysis

20. Knoevenagel Condensation

21. Mannich Reaction

22. Oxidation

23. Paal-Knorr Pyrazole Synthesis

24. Paal-Knorr Pyrrole Synthesis

25. Paal-Knorr Thiophene Synthesis

26. Pechmann Reaction

27. Perkin Synthesis

28. Phillips Reaction

29. Quinoxaline Synthesis

30. Radziszewski Reaction

31. Reduction

32. Reimer-Tiemann Reaction

33. Schiff Base Synthesis (Nucleophilic Addition Reaction)

34. Skraups Synthesis

35. Sulphonamide Synthesis

36. Sulphonate Ester Synthesis (Nucleophilic Substitution Reaction, S_N1)

37. Uracil Synthesis

38. Vilsmeier-Haack Reaction

39. VON Baeyer Synthesis

40. Williamson’s Ether Synthesis (Nucleophilic Substitution of alkaliode/aryloxide S_N2)

41. Wohl-Ziegler Reaction

42. Semi Quantitative Analysis

QUALITATIVE ANALYSIS

43. Analysis of Inorganic Compounds

44. Analysis of Organic Compounds

TITRIMETRIC ANALYSIS

45.   Estimation of Drugs by Acid-Base Titration

46. Estimation of Drugs by Non-Aqueous Titration

47. Estimation of Drugs by Diazotization Titration

48. Estimations of Drugs by Redox Titration

NATURAL PRODUCTS CHEMISTRY

49. Isolation of Plant Alkaloids

50. Isolation of Milk Proteins

51. Isolation of Carbohydrates

52. Isolation of Essential Oils

53. Isolation of Glycosides

54. Isolation of Flavanoids

55. Isolation of Terpenoids

56. Qualitative Analysis of Carbohydrates

57. Qualitative Analysis of Amino Acids and Proteins

58. Qualitative Analysis of Alkaloids

59. Qualitative Analysis of Steroids

60. Qualitative Analysis of Terpenes and Terpenoids

61. Qualitative Analysis of Glycosides

62. Physicochemical Characterization of Natural Products

63. Quantitative Determination of Natural Products

64. Degradation of Natural Products

About the Authors:

T. Durai Ananda Kumar, M. Pharm, Ph.D., is working as an Associate Professor, in the Department of Pharmaceutical Chemistry, JSS College of Pharmacy (a constituent College of JSS Academy of Higher Education and Research), Udhagamandalam, Tamil Nadu. He has teaching experience on Medicinal Chemistry, Computer-Aided Drug Design, Food analysis and Herbal and cosmetic analysis for B. Pharmacy and M. Pharmacy students. He has guided research projects on the structure-based drug design (SBDD) and chemometrics approaches for pharmacy graduates. He has published write number here research articles in peer reviewed journals and has authored six books titled, Elementary Pharmacoinformatics, Experimental Organic Medicinal Chemistry-Principles and Practice, Microwave Assisted Chemistry Experiments (Organic Synthesis, Chemical synthesis & extraction), Current concepts in drug design, Computer aided drug development and Drug design-a conceptual overview. He is on editorial board and reviewer for peer reviewed biomedical journals. The author is life member of Association of Pharmaceutical Teachers of India (APTI) and registered pharmacist of Tamil Nadu State Pharmacy Council.